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Biological & Biomedical Sciences
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Research Paper
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English (U.S.)
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Advancements and Implications of the Corvia Atrial Shunt in Heart Failure Management

Research Paper Instructions:
The paper should cover the following in regard to the Corvia Atrial Shunt device only: 1. What function(s) the device serves, and how it accomplishes these functions. 2. What disorders it can be used to treat/rehabilitate. 3. How it works. This should include a description of the mechanism of the device and its components, mentioning both good qualities of the device, and how it could be improved. 4. Whether it is meant as a permanent device, a rehabilitative (one that is only used for a short while, until the person is better) or something that is used during surgery, etc. 5. How effective is it. This can include percentages of people that use the device where it works effectively, and/or individual testimonials as to its effectiveness. But you should give some indication of how well the device accomplishes its function. 6. The report should also include at least 3 references Note: A great portion of the paper should focus on how this specific device impacts the anatomy and physiology of the heart
Research Paper Sample Content Preview:
Advancements and Implications of the Corvia Atrial Shunt in Heart Failure Management Student’s Name Institution Course # and Name Professor’s Name Submission Date Introduction Heart muscles can become stiff or weak, which impacts their effectiveness and efficiency in pumping blood to the lungs and all parts of the body. When blood flows back into circulatory components, and there is excess pressure in one or more heart chambers for an extended period, symptoms of heart failure set in. Common symptoms include excessive fatigue, shortness of breath, and leg swelling. HF can be life-threatening, and proper medical management is required to help patients live longer and lead better quality lives. Medical care for HF includes pharmacologic, non-pharmacologic, and invasive strategies that aim to limit or reverse its manifestations. Recent medical research on HF management has shifted focus to major non-pharmacologic interventions that limit the rise in pressure in the left atrium. The Corvia Atrial Shunt System (CASS) was designed to decrease high-pressure symptoms in the lungs and heart. This paper will discuss the function of this device, the illnesses it treats or rehabilitates, its mechanism of action, and its effectiveness. Functions of the Device The circulatory system is interconnected with other organ systems, and any device that primarily operates within this system affects the functioning of all body parts. The CASS is implanted in the interatrial septum and exerts its influence by acting on cardiac muscles. The first function of this device is to improve the quality of life for patients with heart failure with perceived ejection fraction (HFpEF). Heart relaxation and contraction impairment cause pressure elevations at the left atrium and pulmonary circulation. The CASS addresses HFpEF by alleviating HF symptoms and improving cardiac function. Normal heart muscle contractions and relaxations due to the presence of this device in the atrial septum reduce the severity of difficulties in breathing, fatigue, and intolerance to strenuousness in HF patients. This reduces the workload on the heart and improves cardiac function. The CASS has a small flexible implant deployed within the interatrial septum using a minimally invasive catheter-based procedure. The device creates a shunt between the two atria that allows blood to flow from a region of higher pressure to a lower-pressure region. The right upper chambers of the heart are responsible for receiving blood and delivering it to the lower chambers to pump to the lungs and all other body parts. Since the left atria are at higher pressure, they will benefit from the pressure influx into the right atria, reducing discomfort in individuals with HF (Litwin et al., 2021). The diversion of blood equalizes the pressure between the two upper heart chambers till equilibrium, reducing the burden on the left side of the heart. The second function of CASS is to enhance cardiac function and exercise tolerance. Patients with HFpEF have strain symptoms when performing their daily duties and during exercise activities. The device improves the heart’s ability to relax and become filled with blood during the resting face of the cardiac cycle. A better diastolic function improves symptoms of heart failure and its overall functioning capacity. The left ventricular filling is essential for maintaining cardiac output and exercise capacity. An improved filling during diastole in patients with HF will make pumping blood to all body parts more efficient, reducing symptoms like dyspnea and fatigue during physical activities (Litwin et al., 2021). Moreover, CASS reduces pulmonary congestion and improves pulmonary hemodynamics, which is essential for performing daily activities and engaging in strenuous exercises. The third function that CASS serves is that it is a non-pharmacologic treatment option for individuals with heart failure. Some patients have less than-average responses to pharmacologic interventions for heart failure and related conditions. Integrating the CASS into their comprehensive treatment plan is a valid consideration in such medical cases. While pharmacotherapy has been the cornerstone of HFpEF management, some patients continue to have severe symptoms even with optimal medical therapy. Moreover, the less invasive nature of CASS makes it a preferred choice for patients who may not be candidates for open heart surgery due to ethical or personal reasons. The procedure of implanting the device in the circulatory system is minimally invasive. It can be performed in a cardiac catheterization laboratory under local anesthesia, with shorter hospital stays an...
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