Pathophysiology of Nephrolithiasis

This week includes an examination of the common disorders of the renal and urologic systems. You will analyze the pathophysiology and pharmacotherapeutic interventions of these disorders and learn to integrate these interventions into patient care. You will also explore the maladaptive and physiological responses, drugs prescribed to treat symptoms and their effects, and the impact of patient factors on pathophysiology and drug responses. Students will:  Analyze the pathophysiology of common disorders.  Compare maladaptive and physiological responses of common disorders.  Analyze types of drugs prescribed to treat symptoms associated with common disorders.  Analyze the impact of patient factors on the pathophysiology of disorders.  Analyze the impact of patient factors on the effects of prescribed drugs for common disorders.  Perform complex case analysis of patients who present with comorbidities.  Analyze methods of patient assessment and education for common disorders. To prepare: • Your Instructor will assign you to one of the following renal or urologic disorders: o nephrolithiasis • Select one of the following patient factors: o genetics o sex o ethnicity o age o individual behavior characteristics, including gender • Reviewing this week’s Resources, consider the pathophysiology as well as the types of drugs that might be used to treat your assigned disorder. • Think about how the factor you selected might impact the pathophysiology of the alteration and effects of prescribed drugs. • Review the clinical care standards and guidelines specific to the assigned disorder. • Consider resulting maladaptive responses for patients with the assigned disorder. Post the following related to the condition you were assigned: • A brief description of the pathophysiology of Nephrolithiasis • Explain how the maladaptive and physiological responses of the disorder might differ. Be specific and provide examples. • Describe the types of drugs that might be prescribed to patients to treat symptoms associated with this disorder and why. • Explain how the patient factor you selected might impact the pathophysiology of the disorder as well as the effects of prescribed drugs you have identified. Be specific and provide examples. Use the Learning Resources and/or best available evidence from current literature to support your post. RESOURCES • McCance, K., & Huether, S. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Elsevier/Mosby. o Chapter 38, “Structure and Function of the Renal and Urologic System” (pp. 1228–1245) o Chapter 39, “Alterations of Renal and Urinary Tract Function” (pp. 1246–1277) • American Academy of Neurology. (2019). Policy and guidelines: Multiple sclerosisLinks to an external site.. Retrieved from https://www(dot)aan(dot)com/Guidelines/home/ByTopic?topicId=18 Note: This link brings you to a list of search results for multiple sclerosis policy and guidelines. Scroll down to see the results. • American College of Physicians. (2014). ACP releases guideline on screening, monitoring, and treatment of stage 1 to 3 chronic kidney diseaseLinks to an external site.. American Family Physician, 90(2), 121–122. Retrieved from https://www(dot)aafp(dot)org/pubs/afp/issues/2014/0715/p121.html • American Family Physician. (2010). Diagnosis and treatment of urethritis in menLinks to an external site.. Retrieved from https://www(dot)aafp(dot)org/afp/2010/0401/p873.html • Huang, W. J., Chen, W. W., & Zhang, X. (2017). Multiple sclerosis: Pathology, diagnosis and treatmentsLinks to an external site.. Experimental and Therapeutic Medicine, 13(6), 3163–3166. https://go(dot)openathens(dot)net/redirector/waldenu.edu?url=https://doi(dot)org/10.3892/etm.2017.4410 • National Multiple Sclerosis Society. (n.d.). MedicationsLinks to an external site.. Retrieved September 12, 2019, from https://www(dot)nationalmssociety(dot)org/Treating-MS/Medications • Portis, A. J., & Sundaram, C. P. (2001). Diagnosis and initial management of kidney stonesLinks to an external site.. American Family Physician, 63(7), 1329–1339. Retrieved from https://www(dot)aafp(dot)org/afp/2001/0401/p1329.htm