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Literature Review Essay
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please see attachment article must be current 5 yrs or less old and peer reviewed. Please also note the web address that th e article were retrieved as this is my final capstone project work please use you expertise in this paper thank you appreciated us the same 15 article to do critique and appraisal please arrange the article in alphabetical order thank you
This checklist is designed to help students organize the weekly exercises/assignments to be completed as preparation for the final capstone project proposal. This checklist will also serve as a communication tool between students and faculty. Comments, feedback, and grading for modules 1-4 will be documented using this checklist.
Analyze and appraise each of the 15 articles identified in module 1. (15 articles).
Analysis organized using the sample provided in “Sample Format for Review of Literature.”
Identified a theory that can be used to support proposed solution.
Main components of theory described.
Rationale for selecting theory provided.
Discussed how theory works to support proposed solution.
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Literature Review
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Article 1: Giannoni, M. F., Ciatti, R., Capaccia, L., Ruggiero, M., Dauri, M., & Mariani, P. P (2009). Total Knee Replacement: Prevention of Deep-Vein Thrombosis Using Pharmacological (Low-Molecular-Weight Heparin) and Mechanical (Intermittent Foot Sole Pump System) Combined Prophylaxis. Preliminary Results.
Summary of article: Giannoni et al. (2009) delved to establish the role of combined pharmacological and mechanical prophylaxis in preventing deep venous thrombosis following total knee replacement. Research elements: the researchers applied prospective case series study, and a total of 38 total knee replacement procedures were carried out on 34 patients, and four patients had bilateral TKR. The researchers gave patients injections of nadroparin calcium and these patients were then observed for 15 days. Outcomes/research results: the results obtained by Giannoni et al (2009) showed that nadroparin calcium reduced the incidence of DVT substantially. Significance to nursing and patient care: the findings of the study implied that nadroparin is effective in preventing DVT after TKR. As such, nadroparin should be the drug of choice by nurses in the prevention of DVT infections following TKR.
Article 2: Blanchard, Y., Meuwly, P., Leyvraz, M., Miron., Bounameaux, H., Hoffmeyer, P., Didier, D., & Schneider, P. (2010). Prevention of Deep-Vein Thrombosis after Total Knee Replacement. The Journal of Bone and Joint Surgery.
Summary of article: the best possible regime of antithrombotic prophylaxis for patients going through TKA is yet to be determined. Some surgeons employ LMWH which were chiefly developed for total hip arthroplasty, whilst other surgeons use intermittent pneumatic compression (Blanchard et al., 2010). The authors compared the safety as well as effectiveness of these 2 methods. Research elements: the researchers carried out a randomized study to compare these 2 techniques with blinded assessment of the endpoint by phlebography. A total of 130 patients were randomized who had been scheduled for elective total knee arthroplasty. A total of 108 patients consisting of 48 in the mechanical prophylaxis group and 60 in the LMWH group had phlebography 8 of twelve days following surgery. Out of the 47 patients who had DVT, 16 of them had LMWH and 31 of them had mechanical prophylaxis. Outcomes/research results: the dissimilarity between the 2 groups was very substantial. Significance to nursing and patient care: One every day subcutaneous injection of LMWH also known as calcium nadroparin in a weight-adjusted, fixed dose scheme is superior and safer relative to intermittent pneumatic compression of the foot for thromboprophylaxis following total knee arthroplasty (Blanchard et al., 2010).
Article 3: Warwick, D. (2012). Prevention of Venous Thromboembolism in Total Knee and Hip Replacement. Circulation.
Summary of article: there are a number of options for reducing venous thromboembolism following knee replacement procedure. Some of these options include neuraxial anesthesia, older oral agents such as warfarin and aspirin, direct thrombin inhibitors as well as injectable agents like LMWH. LMWH is the most effective (Warwick, 2012). Research elements: in this article, the author basically reviews the available options and evidence in regards to the agents that could be used in reducing venous thromboembolism (VTE) after one has undergone knee arthroplasty. Outcomes/research results: LMWH is very effective in reducing VTE following arthroplasty surgery and does not carry any unacceptable bleeding risk. Significance to nursing and patient care: LMWH should be the preferred medication for the prevention of DVT following total knee arthroplasty or total knee replacement.
Article 4: Duplaga, B. A., Pharm, D., Christina, W., & Edith, N. (2009). Dosing and Monitoring of Low-Molecular-Weight Heparins in Special Populations. Pharmacotherapy; 21(2):218-234.
Summary of article: due to several meta-analyses and clinical trials that support the comparative safety and superior effectiveness of LMWHs relative to unfractionated heparin, low-molecular-weight heparins are emerging as the optimal antithrombotic agents in preventing and treating PE and DVT (Duplaga et al., 2009). Research elements: the researchers explored the various low-molecular-weight heparins that have been developed around the world. A variety of low-molecular-weight heparins are obtained from standard unfractionated heparin through various techniques of enzymatic depolymerization or controlled chemical. Outcomes/research results: relative trials demonstrate that LMWHs have superior safety and efficacy relative to UFHs in both TKR and hip replacement surgery. There are differences among various LMWHs. Significance to nursing and patient care: the choice of low-molecular-weight heparin medication has to be based upon clinical trial evidence for each low-molecular-weight heparin for a particular indication.
Article 5: Shawabkeh, J. S., Ghnaimat, M. M., & Hijazi, A. M. (2009). Pharmacologic Prophylaxis and Treatment and Treatment of Venous Thromboembolism after Knee Arthroplasty.
Summary of article: Shawabkeh, Ghnaimat and Hijazi (2009) in their study aimed at assessing the effectiveness of low-molecular-weight heparins (LMWH), warfarin and unfractionated heparin utilized for preventing venous thromboembolism in total knee arthroplasty (Shawabkeh et al., 2009). Research elements: a total of sixty patients were included in this research. These patients were separated into 3 groups each with 20 patients. The incidence of symptomatic DVT or PE was recorded in the initial 30 days following the surgery at a regular follow-up visit. Outcomes/research results: There was a considerably low prevalence of PE and DVT in patients who used low-molecular-weight heparins as prophylaxis compared to those who used unfractionated heparin (Shawabkeh et al., 2009). Significance to nursing and patient care: the findings of their study indicated that LMWH is effective in preventing DVT. As such, it should be used widely by nurses in preventing DVT in patients who have undergone TKA or TKR.
Article 6: Nocolaides, A. N., Fareed, J., Kakkar, A., Breddin, H. K., Goldhaber, S. Z., Kakkar, V. V., Michiels, J. J., Myers, K., Samana, M., Sasahara, A., & Kalodiki, E. (2010). Prevention and Treatment of Venous Thromboembolism. International Consensus Statement. Int Angiol; 25:101-161.
Summary of article: the relationship between the occurrence of symptomatic and asymptomatic VTE including PE is well-known. At present, regulatory bodies in North America and Europe regard the several low-molecular-weight heparins as distinct medication products. LMWH was compared with other medications in the prevention of DVT following total knee arthroplasty (Nocolaides et al., 2010). Research elements: a randomized controlled study was carried out in a placebo and LMWH group. Outcomes/research results: LMWH was more effective relative to placebo; it decreased venographically detected DVT from 65 percent in the placebo group to just 19 percent in the LMWH group. Significance to nursing and patient care: LMWH should be employed by surgeons with appropriate the dosage 6 hours after TKR surgery to prevent prevention since the study proved that it is more effective than warfarin or LDUH.
Article 7: Argun, M., Oner, M., Saglamoglu, M., Karaman, I., Guney, A., Halici, M., & Kafadar, I. H. (2013). Fondaparinux Versus Nadroparin for Prevention of Venous Thromboembolism after Elective Hip and Knee Arthroplasty.
Summary of article: in this article, the researchers report on their research study. Argun et al. (2013) conducted a study to assess the safety and efficacy of nadroparin relative to fondaparinux for preventing venous thromboembolism following arthroplasty. Research elements: the researchers randomized a total of 115 patients into 2 treatment groups. Group I patients were provided with fondaparinux whilst patients in Group II were given nadroparin. Measurements were done on the 1st day, 5th day and 21st day. The investigators assessed the wound area with a subjective visual analog scale. Outcomes/research results: the clinical biochemical tests, blood counts, as well as coagulation tests did not exhibit statistically substantial dissimilarities between the 2 groups.Significance to nursing and patient care: in the absence of fondaparinux, it is recommended that nurses should use nadroparin since its efficacy is almost similar to that of fondaparinux.
Article 8: Thirugnanam, S., Pinto, R., Cook, D., Geerts, W. H., & Fowler, R. A. (2012). Economic Analyses of Venous Thromboembolism Prevention Strategies in Hospitalized Patients: A Systematic Review. Critical Care.
Summary of article: the authors carried out a systematic review of economic analyses of the prevention of venous thromboembolism (VTE) in hospitalized patients in order to inform policymakers as well as clinicians regarding the cost-effectiveness and the possible influence of sponsorship (Thirugnanam et al., 2012). Research elements: the researchers searched ACP Journal Club, EMBASE, MEDLINE, Cochrane Databases, as well as Database of Abstracts of Reviews of Effects from the year 1946 to the year 2011. Data was extracted on study efficacy, characteristics, costs and quality. From 5,180 studies that were identified, 39 satisfied quality as well as eligibility criteria. Outcomes/research results: LMWHs is one of the most effective and inexpensively medications for the prevention of VTE in hospitalized patients. Significance to nursing and patient care: nurses should recommend LMWH drugs to their patients since they are both inexpensive and effectual in the prevention of DVT.
Article 9: Wang, C. J., Wang, J. W., Weng, L. H., Hsu, C. C., Huang, C. C., & Yu, P. C. (2011). Prevention of Deep-Vein Thrombosis after Total Knee Arthroplasty in Asian Patien...
Student:
Professor:
Course title:
Date:
Article 1: Giannoni, M. F., Ciatti, R., Capaccia, L., Ruggiero, M., Dauri, M., & Mariani, P. P (2009). Total Knee Replacement: Prevention of Deep-Vein Thrombosis Using Pharmacological (Low-Molecular-Weight Heparin) and Mechanical (Intermittent Foot Sole Pump System) Combined Prophylaxis. Preliminary Results.
Summary of article: Giannoni et al. (2009) delved to establish the role of combined pharmacological and mechanical prophylaxis in preventing deep venous thrombosis following total knee replacement. Research elements: the researchers applied prospective case series study, and a total of 38 total knee replacement procedures were carried out on 34 patients, and four patients had bilateral TKR. The researchers gave patients injections of nadroparin calcium and these patients were then observed for 15 days. Outcomes/research results: the results obtained by Giannoni et al (2009) showed that nadroparin calcium reduced the incidence of DVT substantially. Significance to nursing and patient care: the findings of the study implied that nadroparin is effective in preventing DVT after TKR. As such, nadroparin should be the drug of choice by nurses in the prevention of DVT infections following TKR.
Article 2: Blanchard, Y., Meuwly, P., Leyvraz, M., Miron., Bounameaux, H., Hoffmeyer, P., Didier, D., & Schneider, P. (2010). Prevention of Deep-Vein Thrombosis after Total Knee Replacement. The Journal of Bone and Joint Surgery.
Summary of article: the best possible regime of antithrombotic prophylaxis for patients going through TKA is yet to be determined. Some surgeons employ LMWH which were chiefly developed for total hip arthroplasty, whilst other surgeons use intermittent pneumatic compression (Blanchard et al., 2010). The authors compared the safety as well as effectiveness of these 2 methods. Research elements: the researchers carried out a randomized study to compare these 2 techniques with blinded assessment of the endpoint by phlebography. A total of 130 patients were randomized who had been scheduled for elective total knee arthroplasty. A total of 108 patients consisting of 48 in the mechanical prophylaxis group and 60 in the LMWH group had phlebography 8 of twelve days following surgery. Out of the 47 patients who had DVT, 16 of them had LMWH and 31 of them had mechanical prophylaxis. Outcomes/research results: the dissimilarity between the 2 groups was very substantial. Significance to nursing and patient care: One every day subcutaneous injection of LMWH also known as calcium nadroparin in a weight-adjusted, fixed dose scheme is superior and safer relative to intermittent pneumatic compression of the foot for thromboprophylaxis following total knee arthroplasty (Blanchard et al., 2010).
Article 3: Warwick, D. (2012). Prevention of Venous Thromboembolism in Total Knee and Hip Replacement. Circulation.
Summary of article: there are a number of options for reducing venous thromboembolism following knee replacement procedure. Some of these options include neuraxial anesthesia, older oral agents such as warfarin and aspirin, direct thrombin inhibitors as well as injectable agents like LMWH. LMWH is the most effective (Warwick, 2012). Research elements: in this article, the author basically reviews the available options and evidence in regards to the agents that could be used in reducing venous thromboembolism (VTE) after one has undergone knee arthroplasty. Outcomes/research results: LMWH is very effective in reducing VTE following arthroplasty surgery and does not carry any unacceptable bleeding risk. Significance to nursing and patient care: LMWH should be the preferred medication for the prevention of DVT following total knee arthroplasty or total knee replacement.
Article 4: Duplaga, B. A., Pharm, D., Christina, W., & Edith, N. (2009). Dosing and Monitoring of Low-Molecular-Weight Heparins in Special Populations. Pharmacotherapy; 21(2):218-234.
Summary of article: due to several meta-analyses and clinical trials that support the comparative safety and superior effectiveness of LMWHs relative to unfractionated heparin, low-molecular-weight heparins are emerging as the optimal antithrombotic agents in preventing and treating PE and DVT (Duplaga et al., 2009). Research elements: the researchers explored the various low-molecular-weight heparins that have been developed around the world. A variety of low-molecular-weight heparins are obtained from standard unfractionated heparin through various techniques of enzymatic depolymerization or controlled chemical. Outcomes/research results: relative trials demonstrate that LMWHs have superior safety and efficacy relative to UFHs in both TKR and hip replacement surgery. There are differences among various LMWHs. Significance to nursing and patient care: the choice of low-molecular-weight heparin medication has to be based upon clinical trial evidence for each low-molecular-weight heparin for a particular indication.
Article 5: Shawabkeh, J. S., Ghnaimat, M. M., & Hijazi, A. M. (2009). Pharmacologic Prophylaxis and Treatment and Treatment of Venous Thromboembolism after Knee Arthroplasty.
Summary of article: Shawabkeh, Ghnaimat and Hijazi (2009) in their study aimed at assessing the effectiveness of low-molecular-weight heparins (LMWH), warfarin and unfractionated heparin utilized for preventing venous thromboembolism in total knee arthroplasty (Shawabkeh et al., 2009). Research elements: a total of sixty patients were included in this research. These patients were separated into 3 groups each with 20 patients. The incidence of symptomatic DVT or PE was recorded in the initial 30 days following the surgery at a regular follow-up visit. Outcomes/research results: There was a considerably low prevalence of PE and DVT in patients who used low-molecular-weight heparins as prophylaxis compared to those who used unfractionated heparin (Shawabkeh et al., 2009). Significance to nursing and patient care: the findings of their study indicated that LMWH is effective in preventing DVT. As such, it should be used widely by nurses in preventing DVT in patients who have undergone TKA or TKR.
Article 6: Nocolaides, A. N., Fareed, J., Kakkar, A., Breddin, H. K., Goldhaber, S. Z., Kakkar, V. V., Michiels, J. J., Myers, K., Samana, M., Sasahara, A., & Kalodiki, E. (2010). Prevention and Treatment of Venous Thromboembolism. International Consensus Statement. Int Angiol; 25:101-161.
Summary of article: the relationship between the occurrence of symptomatic and asymptomatic VTE including PE is well-known. At present, regulatory bodies in North America and Europe regard the several low-molecular-weight heparins as distinct medication products. LMWH was compared with other medications in the prevention of DVT following total knee arthroplasty (Nocolaides et al., 2010). Research elements: a randomized controlled study was carried out in a placebo and LMWH group. Outcomes/research results: LMWH was more effective relative to placebo; it decreased venographically detected DVT from 65 percent in the placebo group to just 19 percent in the LMWH group. Significance to nursing and patient care: LMWH should be employed by surgeons with appropriate the dosage 6 hours after TKR surgery to prevent prevention since the study proved that it is more effective than warfarin or LDUH.
Article 7: Argun, M., Oner, M., Saglamoglu, M., Karaman, I., Guney, A., Halici, M., & Kafadar, I. H. (2013). Fondaparinux Versus Nadroparin for Prevention of Venous Thromboembolism after Elective Hip and Knee Arthroplasty.
Summary of article: in this article, the researchers report on their research study. Argun et al. (2013) conducted a study to assess the safety and efficacy of nadroparin relative to fondaparinux for preventing venous thromboembolism following arthroplasty. Research elements: the researchers randomized a total of 115 patients into 2 treatment groups. Group I patients were provided with fondaparinux whilst patients in Group II were given nadroparin. Measurements were done on the 1st day, 5th day and 21st day. The investigators assessed the wound area with a subjective visual analog scale. Outcomes/research results: the clinical biochemical tests, blood counts, as well as coagulation tests did not exhibit statistically substantial dissimilarities between the 2 groups.Significance to nursing and patient care: in the absence of fondaparinux, it is recommended that nurses should use nadroparin since its efficacy is almost similar to that of fondaparinux.
Article 8: Thirugnanam, S., Pinto, R., Cook, D., Geerts, W. H., & Fowler, R. A. (2012). Economic Analyses of Venous Thromboembolism Prevention Strategies in Hospitalized Patients: A Systematic Review. Critical Care.
Summary of article: the authors carried out a systematic review of economic analyses of the prevention of venous thromboembolism (VTE) in hospitalized patients in order to inform policymakers as well as clinicians regarding the cost-effectiveness and the possible influence of sponsorship (Thirugnanam et al., 2012). Research elements: the researchers searched ACP Journal Club, EMBASE, MEDLINE, Cochrane Databases, as well as Database of Abstracts of Reviews of Effects from the year 1946 to the year 2011. Data was extracted on study efficacy, characteristics, costs and quality. From 5,180 studies that were identified, 39 satisfied quality as well as eligibility criteria. Outcomes/research results: LMWHs is one of the most effective and inexpensively medications for the prevention of VTE in hospitalized patients. Significance to nursing and patient care: nurses should recommend LMWH drugs to their patients since they are both inexpensive and effectual in the prevention of DVT.
Article 9: Wang, C. J., Wang, J. W., Weng, L. H., Hsu, C. C., Huang, C. C., & Yu, P. C. (2011). Prevention of Deep-Vein Thrombosis after Total Knee Arthroplasty in Asian Patien...
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