Research Ethics And Evaluating Quantitative Research

A Randomized Controlled Trial on Pressure Ulcers Management Student’s Name Institution Course Code and Title Professor Date A Randomized Controlled Trial on Pressure Ulcers Management The study design assessed and compared the outcomes, costs, and clinical effectiveness of high-specification foam mattresses (HFMs) and alternating pressure mattresses (APMs) among adult inpatients at risk for pressure injury development. Random sampling was appropriate to assign 2029 high-risk adult inpatients to HFMs or APMs. The researchers avoided systematic bias by minimization with random elements and allocation concealment. The researchers accounted for losses from randomization time to when participants developed a new pressure ulcer category in 60 days. They used intention-to-treat analysis by following up 30 days after treatment. It was impossible to blind the participants and investigators because of the mattresses’ appearance. However, the researchers blinded 10% of the sample population who had skin assessments by an investigator and applied a central blind review of photographs to avoid the risk of bias. All participants were acutely ill inpatients, ≥ 8 years old, had category I pressure ulcers or pain at the site, and were bed/chair bound. They had no differences that could af...