Literature Review: Table of Evidence. Research Proposal.
The purpose of this assignment is to gather research to support your evidence-based project proposal. The research must be sufficient, compelling, relevant, and peer-reviewed professional journal articles. Complete the following:
Refer to your problem statement and proposed topic to search for evidence-based research that supports your proposed project.
Find a minimum of 12 peer-reviewed journal articles that support your proposed topic. The articles must have been published within the last 5 years. You may begin with the reference list you created in Topic 1.
Review the "Rapid Critical Appraisal Checklists," located in Appendix B of the textbook and create a checklist or table to help evaluate the evidence and validity of each study. The specific checklist you choose will be determined by the type of evidence within the resource.
Once you have determined the validity and reliability of the article, use the "Literature Review: Table of Evidence" worksheet to document your articles. This table outlines the attributes of each study and documents the evidence that supports your proposed project. Using a summary table allows you to be more concise in your narrative description. Only research studies used to support your intervention are summarized in this table. You will refer to this table when you write your literature review, and as you develop your proposed solution in support of your intervention.
The "Rapid Critical Appraisal Checklists" and "Literature Review: Table of Evidence" submitted for this assignment are required as part of the appendices in the final paper.
While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.
This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.
You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.
In HIV-serodiscordant couples, how does pre-exposure prophylaxis treatment education compare to the absence of pre-exposure prophylaxis treatment education influence prevention of infection and reduction of transmission in the next three months.
Student Name:
-635513080In HIV-serodiscordant couples, how does pre-exposure prophylaxis treatment education compare to the absence of pre-exposure prophylaxis treatment education influence prevention of infection and reduction of transmission in the next three months.In HIV-serodiscordant couples, how does pre-exposure prophylaxis treatment education compare to the absence of pre-exposure prophylaxis treatment education influence prevention of infection and reduction of transmission in the next three months.Problem Statement:
Criteria
Article 1
Article 2
Article 3
Article 4
Article 5
APA-Formatted Peer-Reviewed Article Citation With Permalink
Frankis, J., Young, I., Flowers, P., & McDaid, L. (2016). Who will use pre-exposure prophylaxis (PrEP) and why?: understanding PrEP awareness and acceptability amongst men who have sex with men in the UK–a mixed methods study. Plos one, 11(4), e0151385.
Mitchell, J. W., Lee, J. Y., Woodyatt, C., Bauermeister, J., Sullivan, P., & Stephenson, R. (2016). HIV-negative male couples’ attitudes about pre-exposure prophylaxis (PrEP) and using PrEP with a sexual agreement. AIDS care, 28(8), 994-999.
Gamarel, K. E., & Golub, S. A. (2015). Intimacy motivations and pre-exposure prophylaxis (PrEP) adoption intentions among HIV-negative men who have sex with men (MSM) in romantic relationships. Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 49(2), 177–186. https://doi.org/10.1007/s12160-014-9646-3
Baeten, J. M., Heffron, R., Kidoguchi, L., Mugo, N. R., Katabira, E., Bukusi, E. A., ... & Bulya, N. (2016). Integrated delivery of antiretroviral treatment and pre-exposure prophylaxis to HIV-1–serodiscordant couples: a prospective implementation study in Kenya and Uganda. PLoS medicine, 13(8), e1002099.
Mayer, K. H., Safren, S. A., Elsesser, S. A., Psaros, C., Tinsley, J. P., Marzinke, M., ... & Mimiaga, M. J. (2017). Optimizing pre-exposure antiretroviral prophylaxis adherence in men who have sex with men: results of a pilot randomized controlled trial of “Life-Steps for PrEP”. AIDS and Behavior, 21(5), 1350-1360.
Article Title and Year Published
Who will use pre-exposure prophylaxis (PrEP) and why?.2016.
HIV-negative male couples’ attitudes about pre-exposure prophylaxis (PrEP) and using PrEP with a sexual agreement. 2016.
Intimacy motivations and pre-exposure prophylaxis (PrEP) adoption intentions among HIV-negative men who have sex with men (MSM) in romantic relationships. 2015.
Integrated delivery of antiretroviral treatment and pre-exposure prophylaxis to HIV-1–serodiscordant couples: a prospective implementation study in Kenya and Uganda. 2016.
Optimizing pre-exposure antiretroviral prophylaxis adherence in men who have sex with men: results of a pilot randomized controlled trial of “Life-Steps for PrEP”. 2017.
Research Questions (Qualitative)/Hypothesis (Quantitative), and Purposes/Aim of Study
Examination of the extent of acceptability of oral pre-exposure prophylaxis (PrEP) as well as treatment as prevention (TasP) for HIV amongst potential users
Study focuses on providing a broad overview of the available research, rather than assessing only the quality
To examine the attitude of the HIV-negative male couples’ toward PrEP use, alongside application of PrEP on the platform of sexual agreement
Assessment of PrEP adoption intentions
How likely do participants think you are to get HIV in your lifetime?
To evaluate the extent to which delivery model is implemented. This entails the level of uptake, adherence, continuation, alongside safety
Description of the process of development of a PrEP adherence intervention
Design (Quantitative, Qualitative, or Other)
Quantitative surveys
Qualitative approach by use of in-depth interviews
Cross-sectional study and in-depth interview
Qualitative approach
Qualitative approach
Setting/Sample
n = 690 MSM, Scotland
29 HIV-negative male couples from Atlanta or Detroit
New York City
Sample included HIV-negative MSM (n = 164)
Kenya and Uganda region.
1,013 heterosexual HIV-1-serodiscordant couples
N=50
Methods: Intervention/Instruments
Questionnaire
Questionnaire
Questionnaire
Interview questionnaire
Questionnaire
Analysis
Descriptive statistics and multivariate logistic regression
Thematic analysis
Bivariate analyses
Thematic analysis
Regression
Key Findings
There was significant level of interest on the use of PrEP amongst MSM who reported HIV risk behaviors
Majority appear to be supportive of PrEP and associated purposes focused on assisting other male couples’ towards reduction of their probability to contract HIV
Higher HIV risk perception concerning
condomless sex,
The implementation of the practical delivery proves feasible providing high uptake as well as adherence and is capable of virtual elimination of HIV1- transmission. The approach applicable proved to be highly effective recording very low levels of HIV-1 transmission rates
Increase in PrEP adherence after intervention
Recommendations
There is need for elaborate support upon introduction of PrEP, such entails a key online element, that ensures existence of equity of awareness across different MSM groups
There should be adequate improvement on informational messaging system as well as use of promotional efforts concerning PrEP as found amongst HIV-negative male couples who may be beneficiaries
Relationship dynamics should be incorporated into biomedical strategies
Intensified counselling should be prioritized
The future research should identify PrEP users with low adherence for enhanced adherence counseling
Explanation of How the Article Supports Your Identified Barrier or Issue in Health Care
The nature of transparency and consistency concerning the presentation of PrEP to participants is therefore critical to understanding of the nature of interventions applicable to our study
Provides the study with nature of likelihood of future PrEP uptake
Relationship dynamics considered as a promising avenue for research and intervention
The findings from the article helps in providing importance on the high level of PrEP adherence and active adherence monitoring.
Help the study in determination of optimal implementation strategies for interventions that maximizes PrEP effectiveness.
Criteria
Article 1
Article 2
Article 3
Article 4
Article 5
APA-Formatted Peer-Reviewed Article Citation With Permalink
Shrestha, R., & Copenhaver, M. (2018). Exploring the use of pre-exposure prophylaxis (PrEP) for HIV prevention among high-risk people who use drugs in treatment. Frontiers in public health, 6, 195.
Bazzi, A. R., Biancarelli, D. L., Childs, E., Drainoni, M. L., Edeza, A., Salhaney, P., ... & Biello, K. B. (2018). Limited knowledge and mixed interest in pre-exposure prophylaxis for HIV prevention among people who inject drugs. AIDS patient care and STDs, 32(12), 529-537.
Mugwanya, K. K., Irungu, E., Bukusi, E., Mugo, N. R., Odoyo, J., Wamoni, E., ... & Barnabee, G. (2018). Scale up of PrEP integrated in public health HIV care clinics: a protocol for a stepped-wedge cluster-randomized rollout in Kenya. Implementation Science, 13(1), 118.
Ahouada, C., Diabaté, S., Mondor, M., Hessou, S., Guédou, F. A., Béhanzin, L., ... & Alary, M. (2020). Acceptability of pre-exposure prophylaxis for HIV prevention: facilitators, barriers and impact on sexual risk behaviors among men who have sex with men in Benin. BMC Public Health, 20(1), 1-17.
Devarajan, S., Sales, J. M., Hunt, M., & Comeau, D. L. (2020). PrEP and sexual well-being: a...
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