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2 pages/≈550 words
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APA
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Health, Medicine, Nursing
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Other (Not Listed)
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English (U.S.)
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Use a creative, visually concept map to explore the listed agonist spectrum and consider the action and receptor of each. (Agonist, Partial agonist, Antagonist, Inverse agonist)

Other (Not Listed) Instructions:
Describe the different characteristics of the four agonists and how each mediates distinct biological activities. Include proposed mechanisms and the receptor it is targeting. Identify how the P450 enzyme system plays a role in the body's absorption, distribution, and clearance of medication. Scavenge the literature after describing each agonist on the spectrum for research that is based on the medications in the table below. Apply the medications to the appropriate agonist on the agonist spectrum in your Concept Map. Medications Oxycodone Brexpiprazole Haloperidol Naloxone Aripiprazole Amphetamine Risperidone Pimavanserin
Other (Not Listed) Sample Content Preview:
Concept Map and Agonist Description Student’s Name Professor’s Name Institutional Affiliations Course Name and Number Due Date Concept Map and Agonist Description Clinicians recognize the importance of understanding the specific actions of drugs for treating varied health issues. According to Stahl (2021), the agonist spectrum highlights one of the diverse ways of learning how medications interact with “the G-protein-linked receptors” (36). Thus, the concept map (Figure 1) demonstrates how each agonist subtype triggers specific biological activities, leading to particular patients’ outcomes.  Figure 1. Agonist Spectrum Concept Map Agonist medications imitate neurotransmitters through their receptor-stimulating capabilities. Page and Pitchford (2021) indicate that this drug category presents receptor-binding features. The conformational change it triggers initiates second messager synthesis, leading to optimum signal transduction. They produce this effect through neurotransmitter site binding on the G-protein receptor or indirectly boosting the natural transmitters’ levels (Stahl, 2021). Thus, such characteristics make these medications ideal for restoring signal transduction and stimulating disease-related symptoms. Other medications demonstrate receptor-stimulating abilities but remain inadequate to meet comparable degrees to those displayed by naturally occurring neurotransmitters. Stahl (2021) describes these medications as partial agonists characterized by the production of significant signal transduction that, although thwarted by full agonists, remains above zero. The author also terms them as stabilizers due to their ability to solve a psychiatric issue by stabilizing aspects such as unstable neurotransmissions. Thus, they also target the G-protein-linked receptors similar to the agonists. Their only variation is the minimized action levels. In other...
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