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Health, Medicine, Nursing
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Topic:
Microscopic Anatomy and Organization of Skeletal Muscle.
Essay Instructions:
1) Describe the banding pattern of a myofibril, including the Z-disc, H-zone, I-band, A-band, and M-line.
2) Describe the structure of a neuromuscular junction and explain its role in the control of muscle function.
Essay Sample Content Preview:
Microscopic Anatomy and Organization of Skeletal Muscle
Name CourseInstructor Date
1 Describe the banding pattern of a myofibril, including the Z-disc, H-zone, I-band, A-band, and M-line.
The skeletal muscle is made up of relatively large, long cylindrical cells (fibers) (Marieb & Smith, 2016). The skeletal muscle cell is striated. When observed with the light microscope, bands of light and dark patterns are arranged next to the cell's major axis. This banding is a result of the superposition of the cytoskeletal filaments that form the myofibrils. The dark bands are called A-band because of anisotropy. This occurs in the deflection of light when viewed with a polarized light microscope) and the alternating light I-band, due to isotropy in the deflection of light). Inside both bands, there are dividing lines called Z-disc and H-zone. Z disks have a typical zig-zag shape when viewed with the electron microscope. The H disk has another darker i...
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