Knowledge Check on Pediatrics: Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia
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Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia is a malignant disease that affects the blood and the bone marrow. It mainly affects the spongy tissue of the bone where blood cells are made, that is, the bone marrow (Rafei et al., 2019). Specifically, the condition leads to the proliferation of immature lymphocytes, also known as lymphoid precursors. These immature lymphocytes replace the normal hematopoietic cells. The word acute is used to describe since the production of immature blood cells occurs rapidly. This cancer is characterized by bleeding of the gums, feeling some pain in the bones, pale skin, and general body weakness, among others. Evidence has shown that ALL is the most common type of cancer affecting children (Pui, 2020). However, there is a high chance of cure with appropriate treatment.
Acute lymphoblastic leukemia occurs when mutations occur in the genetic material that codes for cell growth and development (Kato & Manabe, 2018). Under normal circumstances, this DNA material re...