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Health, Medicine, Nursing
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Essay
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English (U.S.)
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Topic:
Ion channels and G proteins
Essay Instructions:
• Explain the difference between ion channels and G proteins as they relate to signal transduction and targets of medications.
• How would you answer the following patient question:
My grandmother has a mental illness. I have the same genes as her. Will I also get the same mental illness?
Note: Your response needs to be supported and validated by three (3) scholarly peer-reviewed resources located outside of your course Learning Resources.
Essay Sample Content Preview:
Ion Channels and G Proteins
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Ion Channels and G Proteins
Ion channels comprise membrane proteins, which permit the passage of ions (including potassium, sodium, chloride, and calcium) through the cell membrane. These proteins play a substantial role in creating electrical signals in muscle cells and neurons, monitoring cell volume, and controlling the activities of ions into and out of the cells. Ion channels are also engaged in fast signaling incidences, particularly in impulsive cells, comprising muscle cells and neurons (Hutchings et al., 2019). When a ligand binds to the channel or a transformation in membrane ability occurs, ion channels can open or close, causing changes in ion flux across the membrane, which might activate downstream cellular reaction. Furthermore, most of the drugs target ion channels to control their activity. For instance, research shows that cardiac arrhythmia drugs often target ion channels involved in controlling the heart's electrical activity (Hutchings et al., 2019).
Compared to ion channels, G proteins involve a family of proteins that transmits signals from cell surfa...
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