Folate Deficiency Anemia

Folate Deficiency Anemia
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Folate deficiency anemia
Pathophysiology involves the study of mechanism, manifestations, and conditions associated with a disease CITATION McP12 \l 1033 (McPhee, 2012). Folate deficiency anemia is also known as megaloblastic anemia is an anemic condition caused by the deficiency of folic acid, a type of vitamin B needed by the body to enhance the formation and growth of red blood cells.The description that can explain the pathophysiological mechanism of the anemia is that folate is present in the blood plasma in the basic form of 5-methyl THFA. Folate transporters such as ATP enable the THFA to enter into the cell CITATION Hue12 \l 1033 (Huether, 2012). Since the body does not store large quantities of folate, it is required that an individual should supplement the amount by eating food that have a considerable amount of folic acid. The disease is characterized pathologically by abnormally large red blood cells. The manifestation pathology of folate deficiency involves cell division impairment, homocysteine accumulation, and impaired methylation metabolic reactions. The methylation reactions are involved in regulating gene expression. It is the reason folate deficiency anemia augments chances of neoplastic risks to an individual. Other...